Boris Johnson has resigned as Foreign Secretary amid a growing political crisis over the UK’s Brexit strategy.
He is second senior cabinet minister to quit within hours following Brexit Secretary David Davis’s exit.
His departure came 30 minutes before Theresa May is due to address Parliament about her new Brexit plan, which has angered many Tory MPs.
In a statement, No 10 thanked Mr Johnson for his work and said a replacement would be announced shortly.
The BBC’s political editor Laura Kuenssberg said Mr Johnson’s exit had turned an “embarrassing and difficult situation for the PM into potentially a full-blown crisis”.
She said he was not any ordinary cabinet minister but was the “face” of the Leave campaign during the 2016 referendum and his departure would fuel speculation about a leadership challenge.